Program
6th Max Planck Freiburg Epigenetics Meeting 2022
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Day 1 || Session 1 | Session 2 | Keynote
Day 2 || Session 3 | Poster session | Session 4
Day 3 || Session 5 | Session 6
Day 1 – Wednesday, November 30th, 2022
| 11:30 - 13:00 | Registration |
| 13:00 - 13:10 | Welcome Address |
| Session 1: Cell Type Identities Session Chair: Asifa Akhtar & Thomas Jenuwein | |
|---|---|
| 13:15 - 13:40 | Ali Shilatifard (20 min) Principles of epigenetics and chromatin in development and human disease |
| 13:40 - 14:05 | Bing Ren (20 min) Illuminating the dark matter in human DNA with single-cell epigenomics analysis |
| 14:05 - 14:25 | Simon Elsässer (15 min) Polycomb repressive complex 2 shields naïve human pluripotent cells from trophectoderm differentiation |
| 14:25 - 14:45 | Sebastian Arnold (15 min) Global remodeling of enhancer landscapes for all mesoderm and endoderm lineages is initiated by site-specific BAF recruitment through Tbx factor EOMES |
| 14:45 - 15:10 | Wolf Reik (20 min) Single cell multi-omics landscape of development and ageing |
| 15:15 - 15:45 | Coffee break |
| Session 2: Transcription Regulation Session Chair: Amanda Fischer & Nicola Iovino | |
|---|---|
| 15:45 - 16:10 | Ibrahim Cissé (20 min) Super-resolution imaging of transcription in living cells |
| 16:10 - 16:30 | Philippe Batut (15 min) Genome organization & noncoding transcription control timing of Hox gene expression during development |
| 16:30 - 16:55 | Ana Pombo (20 min) Specialization of 3D genome structure in different cell types and cell states |
| 16:55 - 17:15 | Valérie Hilgers (15 min) Sites of transcription initiation drive mRNA isoform selection |
| 17:15 - 17:40 | Nick Proudfoot (20 min) Defining transcription units across the human genome by nascent transcriptional analysis |
| 17:45 - 19:45 | Dinner |
| Keynote Lecture Session Chair: Asifa Akhtar | |
|---|---|
| 20:00 - 20:50 | Nicole Dubilier Eating your microbiome: nutritional symbioses between chemosynthetic bacteria and marine invertrebrates |
| 21:00 | Reception |
Day 2 – Thursday, December 1st, 2022
| Session 3: Inheritance Session Chair: Ana Pombo & Dirk Schübeler | |
|---|---|
| 09:00 - 09:25 | Asifa Akhtar (20 min) Epigenetic regulation by the MSLs: old complex, new facts |
| 09:25 - 09:50 | Anne Ferguson-Smith (20 min) Mammalian epigenetic inheritance at metastable epialleles – agouti viable yellow revisited |
| 09:50 - 10:10 | Andrew Dimond (15 min) Investigating the retention and dissociation of chromatin factors and transcriptional regulators in mitosis |
| 10:10 - 10:35 | Geeta Narlikar (20 min) Mechanism of the INO80 ATP-dependent chromatin remodeling complex |
| 10:35 - 11:00 | Coffee break |
| 11:00 - 11:20 | Germano Cecere (15 min) Soma-to-germline small RNA transfer promotes intragenerational survival to environmental stress |
| 11:20 - 11:45 | Amanda Fisher (20 min) Epigenetic inheritance and mitosis |
| 11:45 - 12:05 | Nina Cabezas-Wallscheid (15 Min) Multilayer-omics analysis reveals a non-classical retinoic acid signaling axis that regulates hematopoietic stem cell identity |
| 12:05 - 12:30 | Dónal O’Carroll (20 min) piRNA-directed DNA methylation during mammalian germline development |
| 12:30 - 14:00 | Lunch break |
| 14:00 - 16:00 | Poster session |
| Session 4: Cancer and Disease Sesson Chair: Geeta Narlikar & Dónal O’Carroll | |
|---|---|
| 16:00 - 16:25 | Yang Shi (20 min) Regulation of the dsRNA-IFN pathway and discovery of new cancer cell vulnerability genes – an update |
| 16:25 - 16:45 | Luigia Pace (15 min) Epigenetic and transcriptional control during CD8 + T cell fate commitment |
| 16:45 - 17:05 | Efrat Shema (15 min) Single-molecule and single-cell epigenetics: decoding the epigenome for cancer research and diagnostics |
| 17:05 - 17:30 | Coffee break |
| 17:30 - 17:55 | Cigall Kadoch (20 min) Structure and function of mammalian SWI/SNF chromatin remodeling complexes in health and disease |
| 17:55 - 18:15 | Wendy Liu (15 min) Biophysical regulation of macrophage epigenetics in wound healing and disease |
| 18:15 - 18:40 | Andrew Pospisilik (20 min) Control and consequences of intrinsic epigenetic variation |
| 19:00 | Free evening / Christmas market 🎄 |
| 20:30 | Speaker’s Dinner |
Day 3 – Friday, December 2nd, 2022
| Session 5: Genome Organization Session Chair: Cigall Kadoch & Andrew Pospisilik | |
|---|---|
| 09:00 - 09:25 | Rob Martienssen (20 min) Chromatin remodeling of histone H3 variants underlies epigenetic inheritance of DNA methylation |
| 09:25 - 09:50 | Andreas Houben (20 min) Plasticity in centromere organization – a holocentromere can consist of only a few centromere units |
| 09:50 - 10:10 | Derek Atkinson (15 min) Jenuwein Lab The identification of the transcriptional coactivator JASPer as a novel Su(var) factor in Drosophila |
| 10:10 - 10:30 | Susan Mango (15 min) Dynamic chromatin during C. elegans embryogenesis |
| 10:30 - 11:00 | Coffee break |
| 11:00 - 11:10 | Poster prize sponsored by MEDEP |
| 11:10 - 11:35 | Bas van Steensel (20 min) Using random scrambling to decode sequence determinants of nuclear organization |
| 11:35 - 11:55 | Peter Meister (15 min) Holocentric genome folding by condensin I |
| 11:55 - 12:20 | Dirk Schübeler (20 min) Beyond motif: guiding sites of transcription factor binding by DNA modification |
| 12:20 - 12:40 | Federica Richina (15 min) DNA methylation turnover in stem cell potency state transitions – a role for Tdg and Smchd1 |
| 12:40 - 13:05 | Roberto Bonasio (20 min) Socially induced brain plasticity and behavioral reprogramming in ants |
| 13:05 - 14:30 | Lunch break |
| Session 6: Higher Order Structuring Session Chair: A. Ferguson-Smith & Ibrahim Cissé | |
|---|---|
| 14:30 - 14:55 | Jeannie Lee (20 min) Epigenetic regulation by RNA G-quadruplexes |
| 14:55 - 15:15 | Raffaella Santoro (15 min) The nucleolus in genome organization and function |
| 15:15 - 15:40 | Nicola Iovino (20 min) Epigenetics of early development |
| 15:40 - 16:05 | Claire Rougeulle (20 min) X chromosome inactivation in primates |
| 16:05 - 16:30 | Coffee break |
| 16:30 - 16:55 | Karim-Jean Armache (20 min) Catalytic and noncatalytic mechanisms of chromatin modifiers |
| 16:55 - 17:15 | Lisa Baumgartner (15 min) The Drosophila ZAD zinc finger protein Kipferl guides Rhino to piRNA clusters |
| 17:15 - 17:35 | Claudia Keller Valsecchi (15 min) Biology of gene dosage in evolution & disease |
| 17:35 - 18:00 | Shraga Schwartz (20 min) Cracking the m6A code |
| 18:00 - 18:25 | Clodagh O’Shea (20 min) Cracking the Nuclear Codes: Finding Order in Chaos |
| 18:30 | Dinner |
| 20:30 | Conference Party |